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KMID : 1189420110240020028
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Journal of Korean Oriental Medical Ophthalmology & Otolaryngology & Dermatology
2011 Volume.24 No. 2 p.28 ~ p.34
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The Effects of Tribulus terrestris on Model of Allergic Rhinitis
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Chou Ching-Yu
Kim Yoon-Bum
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Abstract
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Background and Objectives : Allergic rhinitis is an inflammation or irritation of the mucous membranes that line the nose. Common symptoms include sneezing, a stuffy or runny nose, itchy eyes, nose and throat, and watery eyes. We aimed to determine therapeutic effects of Tribulus terrestris by observing changes of total IgE level and the scratching or rubbing around the nose behavior.
Materials and Methods : Fifteen BALB/c mice were divided into three groups : AR group(allergic rhinitis elicitated), TT group(which ate herbal medicine) and AH group(which ate antihistamine). Allergic rhinitis was induced in the three groups by intraperitoneal and intranasal sensitization with 0.1% ovalbumin solution. Then Tribulus terrestris was orally administered only to the TT group of 28days, while the AH group was given antihistamine. We observed changes of total IgE level and the scratching or rubbing around the nose behavior. We used Kruskal-Wallis test statistically(p<0.05).
Results: 1. Tribulus terrestris showed significantly decreased IgE level on the serum of the rat model. 2. Tribulus terrestris showed significantly decreased scratching or rubbing around the nose behaviors of the rat model.
Conclusion: According to the above results, it is considered that Tribulus terrestris has an inhibitory effect on the process of allergic rhinitis and it can be used in relieving symptoms of allergic rhinitis.
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KEYWORD
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Allergic Rhinitis, Tribulus terrestris, Ovalbumin, Total IgE, nose-scratching
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